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When tobacco and alcohol use are combined, the risk of oral cancer increases 15 times more than non-users of tobacco and alcohol products." Oral cancer can literally wipe the smile off your face…" Studies indicate that there is a definitive link between the use of tobacco products and the development of oral cancer. One study conducted at the University of California, San Francisco, found that more than eight out of ten oral cancer patients were smokers.

 
Tobacco products, heavy use of alcohol and particularly the combined use of both, have been implicated as the main causes of oral cancer. A typical high-risk profile for oral cancer is male, over age 40, who uses tobacco and/or heavy alcohol.About 95 percent of all oral cancers occur in persons over 40 years of age. The average age at the time of diagnosis is about 60. For preventive purposes, it is significant that oral cancer is largely a "lifestyle" disease, meaning the majority of cases are related to tobacco and alcohol use. This usage can be affected by proper education, counselling and treatment.
 
The tobacco industry continues to sponsor research that attempts to confound and deny the issue of tobacco related disease.
 
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